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CD4(+)CD25(+) Regulatory T Cell Depletion Modulates Anxiety and Depression-Like Behaviors in Mice

Stress has been shown to suppress immune function and increase susceptibility to inflammatory disease and psychiatric disease. CD4(+)CD25(+) regulatory T (Treg) cells are prominent in immune regulation. This study was conducted to determine if anti-CD25 antibody (Ab) mediated depletion of Treg cells...

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Detalles Bibliográficos
Autores principales: Kim, Soo-Jeong, Lee, Hyojung, Lee, Gihyun, Oh, Sei-Joong, Shin, Min-Kyu, Shim, Insop, Bae, Hyunsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409145/
https://www.ncbi.nlm.nih.gov/pubmed/22860054
http://dx.doi.org/10.1371/journal.pone.0042054