Efficient Amplification of Chimeric Adenovirus 5/40S Vectors Carrying the Short Fiber Protein of Ad40 in Suspension Cell Cultures

The human adenovirus 40 (Ad40) is a promising tool for gene therapy of intestinal diseases. Since the production of Ad40 in vitro is extremely inefficient, chimeric Adenovirus 5/40S vectors carrying the Ad40 short fiber on the Ad5 capsid have been developed. However, Ad5/40S productivity is low. We...

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Detalles Bibliográficos
Autores principales: Miralles, Marta, Segura, María Mercedes, Puig, Meritxell, Bosch, Assumpció, Chillon, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409147/
https://www.ncbi.nlm.nih.gov/pubmed/22860056
http://dx.doi.org/10.1371/journal.pone.0042073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409147/
https://www.ncbi.nlm.nih.gov/pubmed/22860056
http://dx.doi.org/10.1371/journal.pone.0042073

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