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Effects of Niacin Restriction on Sirtuin and PARP Responses to Photodamage in Human Skin

Sirtuins (SIRTs) and poly(ADP-ribose) polymerases (PARPs), NAD(+)-dependent enzymes, link cellular energy status with responses to environmental stresses. Skin is frequently exposed to the DNA damaging effects of UV irradiation, a known etiology in skin cancer. Thus, understanding the defense mechan...

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Detalles Bibliográficos
Autores principales:	Benavente, Claudia A., Schnell, Stephanie A., Jacobson, Elaine L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409181/ https://www.ncbi.nlm.nih.gov/pubmed/22860104 http://dx.doi.org/10.1371/journal.pone.0042276

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