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Differential Trypanocidal Activity of Novel Macrolide Antibiotics; Correlation to Genetic Lineage

Here we report the systematic study of the anti-trypanocidal activity of some new products derived from S. diastatus on 14 different T. cruzi strains spanning the six genetic lineages of T. cruzi. As the traditional growth inhibition curves giving similar IC(50) showed great differences on antibioti...

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Detalles Bibliográficos
Autores principales: Aquilino, Carolina, Gonzalez Rubio, Maria Luisa, Seco, Elena Maria, Escudero, Leticia, Corvo, Laura, Soto, Manuel, Fresno, Manuel, Malpartida, Francisco, Bonay, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409201/
https://www.ncbi.nlm.nih.gov/pubmed/22859958
http://dx.doi.org/10.1371/journal.pone.0040901