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Cathepsin K-Cre Causes Unexpected Germline Deletion of Genes in Mice
Osteoclasts are terminally differentiated cells that attach to bone and secrete proteases to degrade the bone matrix. The primary protease responsible for the degradation of the organic component of the bone matrix is Cathepsin K, which was largely thought to be unique to osteoclasts. Given its appa...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409209/ https://www.ncbi.nlm.nih.gov/pubmed/22860046 http://dx.doi.org/10.1371/journal.pone.0042005 |