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Perturbation of microRNAs in Rat Heart during Chronic Doxorubicin Treatment

Anti-cancer therapy based on anthracyclines (DNA intercalating Topoisomerase II inhibitors) is limited by adverse effects of these compounds on the cardiovascular system, ultimately causing heart failure. Despite extensive investigations into the effects of doxorubicin on the cardiovascular system,...

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Detalles Bibliográficos
Autores principales: Vacchi-Suzzi, Caterina, Bauer, Yasmina, Berridge, Brian R., Bongiovanni, Sandrine, Gerrish, Kevin, Hamadeh, Hisham K., Letzkus, Martin, Lyon, Jonathan, Moggs, Jonathan, Paules, Richard S., Pognan, François, Staedtler, Frank, Vidgeon-Hart, Martin P., Grenet, Olivier, Couttet, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409211/
https://www.ncbi.nlm.nih.gov/pubmed/22859947
http://dx.doi.org/10.1371/journal.pone.0040395