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GLI2 Regulates TGF-β1 in Human CD4(+) T Cells: Implications in Cancer and HIV Pathogenesis

Elevated levels of the immunoregulatory cytokine TGF-β1 in cancer and HIV infection have been linked to the suppression of protective immune responses. The transcriptional regulation of TGF-β1 is complex and still not completely understood. We report here for the first time that the transcription fa...

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Detalles Bibliográficos
Autores principales: Furler, Robert L., Uittenbogaart, Christel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409217/
https://www.ncbi.nlm.nih.gov/pubmed/22859956
http://dx.doi.org/10.1371/journal.pone.0040874