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GLI2 Regulates TGF-β1 in Human CD4(+) T Cells: Implications in Cancer and HIV Pathogenesis
Elevated levels of the immunoregulatory cytokine TGF-β1 in cancer and HIV infection have been linked to the suppression of protective immune responses. The transcriptional regulation of TGF-β1 is complex and still not completely understood. We report here for the first time that the transcription fa...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409217/ https://www.ncbi.nlm.nih.gov/pubmed/22859956 http://dx.doi.org/10.1371/journal.pone.0040874 |