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Neuronal Transcription Factors Induce Conversion of Human Glioma Cells to Neurons and Inhibit Tumorigenesis

Recent findings have demonstrated that the overexpression of lineage-specific transcription factors induces cell fate changes among diverse cell types. For example, neurons can be generated from mouse and human fibroblasts. It is well known that neurons are terminally differentiated cells that do no...

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Detalles Bibliográficos
Autores principales: Zhao, Junli, He, Hua, Zhou, Kechun, Ren, Yonggang, Shi, Zixiao, Wu, Zhiyuan, Wang, Yizheng, Lu, Yicheng, Jiao, Jianwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409237/
https://www.ncbi.nlm.nih.gov/pubmed/22859994
http://dx.doi.org/10.1371/journal.pone.0041506