Local Arginase Inhibition during Early Reperfusion Mediates Cardioprotection via Increased Nitric Oxide Production

Consumption of L-arginine contributes to reduced bioavailability of nitric oxide (NO) that is critical for the development of ischemia-reperfusion injury. The aim of the study was to determine myocardial arginase expression and activity in ischemic-reperfusion myocardium and whether local inhibition...

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Detalles Bibliográficos
Autores principales: Gonon, Adrian T., Jung, Christian, Katz, Abram, Westerblad, Håkan, Shemyakin, Alexey, Sjöquist, Per-Ove, Lundberg, Jon O., Pernow, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409239/
https://www.ncbi.nlm.nih.gov/pubmed/22860052
http://dx.doi.org/10.1371/journal.pone.0042038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409239/
https://www.ncbi.nlm.nih.gov/pubmed/22860052
http://dx.doi.org/10.1371/journal.pone.0042038

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