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Probing Cocaine-Antibody Interactions in Buffer and Human Serum

BACKGROUND: Despite progress in cocaine immunotherapy, the kinetic and thermodynamic properties of antibodies which bind to cocaine and its metabolites are not well understood. It is also not clear how the interactions between them differ in a complex matrix such as the serum present in the human bo...

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Detalles Bibliográficos
Autores principales: Ramakrishnan, Muthu, Alves De Melo, Fernando, Kinsey, Berma M., Ladbury, John E., Kosten, Thomas R., Orson, Frank M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409241/
https://www.ncbi.nlm.nih.gov/pubmed/22859949
http://dx.doi.org/10.1371/journal.pone.0040518