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Probing Cocaine-Antibody Interactions in Buffer and Human Serum
BACKGROUND: Despite progress in cocaine immunotherapy, the kinetic and thermodynamic properties of antibodies which bind to cocaine and its metabolites are not well understood. It is also not clear how the interactions between them differ in a complex matrix such as the serum present in the human bo...
Autores principales: | Ramakrishnan, Muthu, Alves De Melo, Fernando, Kinsey, Berma M., Ladbury, John E., Kosten, Thomas R., Orson, Frank M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409241/ https://www.ncbi.nlm.nih.gov/pubmed/22859949 http://dx.doi.org/10.1371/journal.pone.0040518 |
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