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Human genomic disease variants: A neutral evolutionary explanation

Many perspectives on the role of evolution in human health include nonempirical assumptions concerning the adaptive evolutionary origins of human diseases. Evolutionary analyses of the increasing wealth of clinical and population genomic data have begun to challenge these presumptions. In order to s...

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Detalles Bibliográficos
Autores principales: Dudley, Joel T., Kim, Yuseob, Liu, Li, Markov, Glenn J., Gerold, Kristyn, Chen, Rong, Butte, Atul J., Kumar, Sudhir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409252/
https://www.ncbi.nlm.nih.gov/pubmed/22665443
http://dx.doi.org/10.1101/gr.133702.111