Neonatal DNA methylation profile in human twins is specified by a complex interplay between intrauterine environmental and genetic factors, subject to tissue-specific influence

Comparison between groups of monozygotic (MZ) and dizygotic (DZ) twins enables an estimation of the relative contribution of genetic and shared and nonshared environmental factors to phenotypic variability. Using DNA methylation profiling of ∼20,000 CpG sites as a phenotype, we have examined discord...

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Detalles Bibliográficos
Autores principales: Gordon, Lavinia, Joo, Jihoon E., Powell, Joseph E., Ollikainen, Miina, Novakovic, Boris, Li, Xin, Andronikos, Roberta, Cruickshank, Mark N., Conneely, Karen N., Smith, Alicia K., Alisch, Reid S., Morley, Ruth, Visscher, Peter M., Craig, Jeffrey M., Saffery, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409253/
https://www.ncbi.nlm.nih.gov/pubmed/22800725
http://dx.doi.org/10.1101/gr.136598.111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409253/
https://www.ncbi.nlm.nih.gov/pubmed/22800725
http://dx.doi.org/10.1101/gr.136598.111

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