Integrative functional genomics identifies an enhancer looping to the SOX9 gene disrupted by the 17q24.3 prostate cancer risk locus

Genome-wide association studies (GWAS) are identifying genetic predisposition to various diseases. The 17q24.3 locus harbors the single nucleotide polymorphism (SNP) rs1859962 that is statistically associated with prostate cancer (PCa). It defines a 130-kb linkage disequilibrium (LD) block that lies...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoyang, Cowper-Sal·lari, Richard, Bailey, Swneke D., Moore, Jason H., Lupien, Mathieu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409257/
https://www.ncbi.nlm.nih.gov/pubmed/22665440
http://dx.doi.org/10.1101/gr.135665.111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409257/
https://www.ncbi.nlm.nih.gov/pubmed/22665440
http://dx.doi.org/10.1101/gr.135665.111

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