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Systematic identification of edited microRNAs in the human brain

Adenosine-to-inosine (A-to-I) editing modifies RNA transcripts from their genomic blueprint. A prerequisite for this process is a double-stranded RNA (dsRNA) structure. Such dsRNAs are formed as part of the microRNA (miRNA) maturation process, and it is therefore expected that miRNAs are affected by...

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Detalles Bibliográficos
Autores principales: Alon, Shahar, Mor, Eyal, Vigneault, Francois, Church, George M., Locatelli, Franco, Galeano, Federica, Gallo, Angela, Shomron, Noam, Eisenberg, Eli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409266/
https://www.ncbi.nlm.nih.gov/pubmed/22499667
http://dx.doi.org/10.1101/gr.131573.111