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Dissection of complex adult traits in a mouse synthetic population

Finding the causative genetic variations that underlie complex adult traits is a significant experimental challenge. The unbiased search strategy of genome-wide association (GWAS) has been used extensively in recent human population studies. These efforts, however, typically find only a minor fracti...

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Detalles Bibliográficos
Autores principales: Burke, David T., Kozloff, Kenneth M., Chen, Shu, West, Joshua L., Wilkowski, Jodi M., Goldstein, Steven A., Miller, Richard A., Galecki, Andrzej T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409268/
https://www.ncbi.nlm.nih.gov/pubmed/22588897
http://dx.doi.org/10.1101/gr.135582.111