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Electrophysiological abnormalities precede overt structural changes in arrhythmogenic right ventricular cardiomyopathy due to mutations in desmoplakin-A combined murine and human study

AIMS: Anecdotal observations suggest that sub-clinical electrophysiological manifestations of arrhythmogenic right ventricular cardiomyopathy (ARVC) develop before detectable structural changes ensue on cardiac imaging. To test this hypothesis, we investigated a murine model with conditional cardiac...

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Detalles Bibliográficos
Autores principales: Gomes, John, Finlay, Malcolm, Ahmed, Akbar K., Ciaccio, Edward J., Asimaki, Angeliki, Saffitz, Jeffrey E., Quarta, Giovanni, Nobles, Muriel, Syrris, Petros, Chaubey, Sanjay, McKenna, William J., Tinker, Andrew, Lambiase, Pier D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409421/
https://www.ncbi.nlm.nih.gov/pubmed/22240500
http://dx.doi.org/10.1093/eurheartj/ehr472