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The chemoattractant chemerin suppresses melanoma by recruiting natural killer cell antitumor defenses

Infiltration of specialized immune cells regulates the growth and survival of neoplasia. Here, in a survey of public whole genome expression datasets we found that the gene for chemerin, a widely expressed endogenous chemoattractant protein, is down-regulated in melanoma as well as other human tumor...

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Detalles Bibliográficos
Autores principales: Pachynski, Russell K., Zabel, Brian A., Kohrt, Holbrook E., Tejeda, Nicole M., Monnier, Justin, Swanson, Christina D., Holzer, Alison K., Gentles, Andrew J., Sperinde, Gizette V., Edalati, Abdolhossein, Hadeiba, Husein A., Alizadeh, Ash A., Butcher, Eugene C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409495/
https://www.ncbi.nlm.nih.gov/pubmed/22753924
http://dx.doi.org/10.1084/jem.20112124