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The chemoattractant chemerin suppresses melanoma by recruiting natural killer cell antitumor defenses
Infiltration of specialized immune cells regulates the growth and survival of neoplasia. Here, in a survey of public whole genome expression datasets we found that the gene for chemerin, a widely expressed endogenous chemoattractant protein, is down-regulated in melanoma as well as other human tumor...
Autores principales: | Pachynski, Russell K., Zabel, Brian A., Kohrt, Holbrook E., Tejeda, Nicole M., Monnier, Justin, Swanson, Christina D., Holzer, Alison K., Gentles, Andrew J., Sperinde, Gizette V., Edalati, Abdolhossein, Hadeiba, Husein A., Alizadeh, Ash A., Butcher, Eugene C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409495/ https://www.ncbi.nlm.nih.gov/pubmed/22753924 http://dx.doi.org/10.1084/jem.20112124 |
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