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A diverse array of gene products are effectors of the type I interferon antiviral response

The type I interferon (IFN) response protects cells from invading viral pathogens. The cellular factors that mediate this defense are the products of interferon-stimulated genes (ISGs). Although hundreds of ISGs have been identified since their discovery over 25 years ago(1,2,3), only few have been...

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Detalles Bibliográficos
Autores principales: Schoggins, John W., Wilson, Sam J., Panis, Maryline, Murphy, Mary Y., Jones, Christopher T., Bieniasz, Paul, Rice, Charles M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409588/
https://www.ncbi.nlm.nih.gov/pubmed/21478870
http://dx.doi.org/10.1038/nature09907