Mitochondrial fusion by pharmacological manipulation impedes somatic cell reprogramming to pluripotency: New insight into the role of mitophagy in cell stemness

Recent studies have suggested a pivotal role for autophagy in stem cell maintenance and differentiation. Reprogramming of somatic cells to induced pluripotent stem cells (iPSCs) has been also suggested to bio-energetically take advantage of mitochondrial autophagy (mitophagy). We have preliminary ad...

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Detalles Bibliográficos
Autores principales: Vazquez-Martin, Alejandro, Cufí, Sílvia, Corominas-Faja, Bruna, Oliveras-Ferraros, Cristina, Vellon, Luciano, Menendez, Javier A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2012
Materias:
Research Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409676/
https://www.ncbi.nlm.nih.gov/pubmed/22713507

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409676/
https://www.ncbi.nlm.nih.gov/pubmed/22713507

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