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Mitochondrial fusion by pharmacological manipulation impedes somatic cell reprogramming to pluripotency: New insight into the role of mitophagy in cell stemness

Recent studies have suggested a pivotal role for autophagy in stem cell maintenance and differentiation. Reprogramming of somatic cells to induced pluripotent stem cells (iPSCs) has been also suggested to bio-energetically take advantage of mitochondrial autophagy (mitophagy). We have preliminary ad...

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Detalles Bibliográficos
Autores principales:	Vazquez-Martin, Alejandro, Cufí, Sílvia, Corominas-Faja, Bruna, Oliveras-Ferraros, Cristina, Vellon, Luciano, Menendez, Javier A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2012
Materias:	Research Perspective
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409676/ https://www.ncbi.nlm.nih.gov/pubmed/22713507

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