Laninamivir Octanoate and Artificial Surfactant Combination Therapy Significantly Increases Survival of Mice Infected with Lethal Influenza H1N1 Virus

BACKGROUND: Patients with influenza virus infection can develop severe pneumonia and acute respiratory distress syndrome (ARDS) which have a high mortality. Influenza virus infection is treated worldwide mainly by neuraminidase inhibitors (NAIs). However, monotherapy with NAIs is insufficient for se...

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Detalles Bibliográficos
Autores principales: Fukushi, Masaya, Yamashita, Makoto, Miyoshi-Akiyama, Tohru, Kubo, Shuku, Yamamoto, Kenji, Kudo, Koichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409853/
https://www.ncbi.nlm.nih.gov/pubmed/22879974
http://dx.doi.org/10.1371/journal.pone.0042419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409853/
https://www.ncbi.nlm.nih.gov/pubmed/22879974
http://dx.doi.org/10.1371/journal.pone.0042419

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