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Analysis of Cyclin D1 in Breast Cancer: A Call to Arms

The oncogenic capabilities of the cell cycle protein cyclin D1 have long been established in a breast cancer setting. The CCND1 gene is amplified in up to 15 % of breast tumors, with overexpression of its corresponding protein found in up to 50 % of cases. While gene amplification is consistently as...

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Detalles Bibliográficos
Autores principales: Tobin, Nicholas P., Bergh, Jonas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Current Science Inc. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410026/
https://www.ncbi.nlm.nih.gov/pubmed/22924091
http://dx.doi.org/10.1007/s12609-012-0083-7