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Distinct roles for direct and indirect pathway striatal neurons in reinforcement

Dopamine signaling is implicated in reinforcement learning, but the neural substrates targeted by dopamine are poorly understood. Here, we bypassed dopamine signaling itself and tested how optogenetic activation of dopamine D1- or D2-receptor-expressing striatal projection neurons influenced reinfor...

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Detalles Bibliográficos
Autores principales: Kravitz, Alexxai V., Tye, Lynne D., Kreitzer, Anatol C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410042/
https://www.ncbi.nlm.nih.gov/pubmed/22544310
http://dx.doi.org/10.1038/nn.3100