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Expansion of bone marrow neutrophils following G-CSF administration in mice results in osteolineage cell apoptosis and mobilization of hematopoietic stem and progenitor cells

Proliferation and differentiation of hematopoietic stem/progenitor cells (HSPC) within bone marrow (BM) niches are regulated by adhesion molecules and cytokines produced by mesenchymal stem/progenitor cells (MPC) and osteoblasts (OB). HSPCs that egresses to peripheral blood are widely used for trans...

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Detalles Bibliográficos
Autores principales: Singh, Pratibha, Hu, Peirong, Hoggatt, Jonathan, Moh, Akira, Pelus, Louis M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410045/
https://www.ncbi.nlm.nih.gov/pubmed/22543963
http://dx.doi.org/10.1038/leu.2012.117