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Variable ligand- and receptor-binding hot spots in key strains of influenza neuraminidase

Influenza A continues to be a major public health concern due to its ability to cause epidemic and pandemic disease outbreaks in humans. Computational investigations of structural dynamics of the major influenza glycoproteins, especially the neuraminidase (NA) enzyme, are able to provide key insight...

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Detalles Bibliográficos
Autores principales: Votapka, Lane, Demir, Özlem, Swift, Robert V, Walker, Ross C, Amaro, Rommie E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Library Publishing Media 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410406/
https://www.ncbi.nlm.nih.gov/pubmed/22872804