Cargando…

Class II formin targeting to the cell cortex by binding PI(3,5)P(2) is essential for polarized growth

Class II formins are key regulators of actin and are essential for polarized plant cell growth. Here, we show that the class II formin N-terminal phosphatase and tensin (PTEN) domain binds phosphoinositide-3,5-bisphosphate (PI(3,5)P(2)). Replacing the PTEN domain with polypeptides of known lipid-bin...

Descripción completa

Detalles Bibliográficos
Autores principales: van Gisbergen, Peter A.C., Li, Ming, Wu, Shu-Zon, Bezanilla, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410418/
https://www.ncbi.nlm.nih.gov/pubmed/22801781
http://dx.doi.org/10.1083/jcb.201112085