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Sds22 and Repo-Man stabilize chromosome segregation by counteracting Aurora B on anaphase kinetochores

During mitotic spindle assembly, Aurora B kinase is part of an error correction mechanism that detaches microtubules from kinetochores that are under low mechanical tension. During anaphase, however, kinetochore–microtubule attachments must be maintained despite a drop of tension after removal of si...

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Detalles Bibliográficos
Autores principales: Wurzenberger, Claudia, Held, Michael, Lampson, Michael A., Poser, Ina, Hyman, Anthony A., Gerlich, Daniel W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410419/
https://www.ncbi.nlm.nih.gov/pubmed/22801782
http://dx.doi.org/10.1083/jcb.201112112