Cargando…

Effects of Perinuclear Chromosome Tethers in the Telomeric URA3/5FOA System Reflect Changes to Gene Silencing and not Nucleotide Metabolism

Telomeres are repetitive DNA sequences that protect the ends of linear chromosomes. Telomeres also recruit histone deacetylase complexes that can then spread along chromosome arms and repress the expression of subtelomeric genes in a process known as telomere position effect (TPE). In the budding ye...

Descripción completa

Detalles Bibliográficos
Autores principales: Poon, Betty P. K., Mekhail, Karim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410493/
https://www.ncbi.nlm.nih.gov/pubmed/22876257
http://dx.doi.org/10.3389/fgene.2012.00144