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Origin, diversity, and maturation of human antiviral antibodies analyzed by high-throughput sequencing

Our understanding of how antibodies are generated and function could help develop effective vaccines and antibody-based therapeutics against viruses such as HIV-1, SARS coronavirus (SARS CoV), and Hendra and Nipah viruses (henipaviruses). Although broadly neutralizing antibodies (bnAbs) against the...

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Detalles Bibliográficos
Autores principales: Prabakaran, Ponraj, Zhu, Zhongyu, Chen, Weizao, Gong, Rui, Feng, Yang, Streaker, Emily, Dimitrov, Dimiter S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410596/
https://www.ncbi.nlm.nih.gov/pubmed/22876240
http://dx.doi.org/10.3389/fmicb.2012.00277