Cargando…
Origin, diversity, and maturation of human antiviral antibodies analyzed by high-throughput sequencing
Our understanding of how antibodies are generated and function could help develop effective vaccines and antibody-based therapeutics against viruses such as HIV-1, SARS coronavirus (SARS CoV), and Hendra and Nipah viruses (henipaviruses). Although broadly neutralizing antibodies (bnAbs) against the...
Autores principales: | Prabakaran, Ponraj, Zhu, Zhongyu, Chen, Weizao, Gong, Rui, Feng, Yang, Streaker, Emily, Dimitrov, Dimiter S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410596/ https://www.ncbi.nlm.nih.gov/pubmed/22876240 http://dx.doi.org/10.3389/fmicb.2012.00277 |
Ejemplares similares
-
454 antibody sequencing - error characterization and correction
por: Prabakaran, Ponraj, et al.
Publicado: (2011) -
The Antibody Germline/Maturation Hypothesis, Elicitation of Broadly Neutralizing Antibodies Against HIV-1 and Cord Blood IgM Repertoires
por: Prabakaran, Ponraj, et al.
Publicado: (2014) -
Characterization of germline antibody libraries from human umbilical cord blood and selection of monoclonal antibodies to viral envelope glycoproteins: Implications for mechanisms of immune evasion and design of vaccine immunogens
por: Chen, Weizao, et al.
Publicado: (2012) -
Human monoclonal antibodies as candidate therapeutics against emerging viruses and HIV-1
por: Zhu, Zhongyu, et al.
Publicado: (2013) -
Antibody Aggregation: Insights from Sequence and Structure
por: Li, Wei, et al.
Publicado: (2016)