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Aldo-Keto Reductases 1B in Endocrinology and Metabolism

The aldose reductase (AR; human AKR1B1/mouse Akr1b3) has been the focus of many research because of its role in diabetic complications. The starting point of these alterations is the massive entry of glucose in polyol pathway where it is converted into sorbitol by this enzyme. However, the issue of...

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Detalles Bibliográficos
Autores principales: Pastel, Emilie, Pointud, Jean-Christophe, Volat, Fanny, Martinez, Antoine, Lefrançois-Martinez, Anne-Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410611/
https://www.ncbi.nlm.nih.gov/pubmed/22876234
http://dx.doi.org/10.3389/fphar.2012.00148