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Delayed expression of cell cycle proteins contributes to astroglial scar formation and chronic inflammation after rat spinal cord contusion

BACKGROUND: Traumatic spinal cord injury (SCI) induces secondary tissue damage that is associated with astrogliosis and inflammation. We previously reported that acute upregulation of a cluster of cell-cycle-related genes contributes to post-mitotic cell death and secondary damage after SCI. However...

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Detalles Bibliográficos
Autores principales: Wu, Junfang, Pajoohesh-Ganji, Ahdeah, Stoica, Bogdan A, Dinizo, Michael, Guanciale, Kelsey, Faden, Alan I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410790/
https://www.ncbi.nlm.nih.gov/pubmed/22784881
http://dx.doi.org/10.1186/1742-2094-9-169