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Multiple Roles and Interactions of Tbx4 and Tbx5 in Development of the Respiratory System

Normal development of the respiratory system is essential for survival and is regulated by multiple genes and signaling pathways. Both Tbx4 and Tbx5 are expressed throughout the mesenchyme of the developing lung and trachea; and, although multiple genes are known to be required in the epithelium, on...

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Detalles Bibliográficos
Autores principales: Arora, Ripla, Metzger, Ross J., Papaioannou, Virginia E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410851/
https://www.ncbi.nlm.nih.gov/pubmed/22876201
http://dx.doi.org/10.1371/journal.pgen.1002866