Uridine Composition of the Poly-U/UC Tract of HCV RNA Defines Non-Self Recognition by RIG-I

Viral infection of mammalian cells triggers the innate immune response through non-self recognition of pathogen associated molecular patterns (PAMPs) in viral nucleic acid. Accurate PAMP discrimination is essential to avoid self recognition that can generate autoimmunity, and therefore should be fac...

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Detalles Bibliográficos
Autores principales: Schnell, Gretja, Loo, Yueh-Ming, Marcotrigiano, Joseph, Gale, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410852/
https://www.ncbi.nlm.nih.gov/pubmed/22912574
http://dx.doi.org/10.1371/journal.ppat.1002839

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410852/
https://www.ncbi.nlm.nih.gov/pubmed/22912574
http://dx.doi.org/10.1371/journal.ppat.1002839

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