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Structural Bases of Coronavirus Attachment to Host Aminopeptidase N and Its Inhibition by Neutralizing Antibodies

The coronaviruses (CoVs) are enveloped viruses of animals and humans associated mostly with enteric and respiratory diseases, such as the severe acute respiratory syndrome and 10–20% of all common colds. A subset of CoVs uses the cell surface aminopeptidase N (APN), a membrane-bound metalloprotease,...

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Detalles Bibliográficos
Autores principales: Reguera, Juan, Santiago, César, Mudgal, Gaurav, Ordoño, Desiderio, Enjuanes, Luis, Casasnovas, José M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410853/
https://www.ncbi.nlm.nih.gov/pubmed/22876187
http://dx.doi.org/10.1371/journal.ppat.1002859