A Positive Feedback Loop Links Opposing Functions of P-TEFb/Cdk9 and Histone H2B Ubiquitylation to Regulate Transcript Elongation in Fission Yeast

Transcript elongation by RNA polymerase II (RNAPII) is accompanied by conserved patterns of histone modification. Whereas histone modifications have established roles in transcription initiation, their functions during elongation are not understood. Mono-ubiquitylation of histone H2B (H2Bub1) plays...

Descripción completa

Detalles Bibliográficos
Autores principales: Sansó, Miriam, Lee, Karen M., Viladevall, Laia, Jacques, Pierre-Étienne, Pagé, Viviane, Nagy, Stephen, Racine, Ariane, St. Amour, Courtney V., Zhang, Chao, Shokat, Kevan M., Schwer, Beate, Robert, François, Fisher, Robert P., Tanny, Jason C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410854/
https://www.ncbi.nlm.nih.gov/pubmed/22876190
http://dx.doi.org/10.1371/journal.pgen.1002822

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410854/
https://www.ncbi.nlm.nih.gov/pubmed/22876190
http://dx.doi.org/10.1371/journal.pgen.1002822

Ejemplares similares