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Mutation Induced Extinction in Finite Populations: Lethal Mutagenesis and Lethal Isolation
Reproduction is inherently risky, in part because genomic replication can introduce new mutations that are usually deleterious toward fitness. This risk is especially severe for organisms whose genomes replicate “semi-conservatively,” e.g. viruses and bacteria, where no master copy of the genome is...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410861/ https://www.ncbi.nlm.nih.gov/pubmed/22876168 http://dx.doi.org/10.1371/journal.pcbi.1002609 |