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Minibrain/Dyrk1a Regulates Food Intake through the Sir2-FOXO-sNPF/NPY Pathway in Drosophila and Mammals

Feeding behavior is one of the most essential activities in animals, which is tightly regulated by neuroendocrine factors. Drosophila melanogaster short neuropeptide F (sNPF) and the mammalian functional homolog neuropeptide Y (NPY) regulate food intake. Understanding the molecular mechanism of sNPF...

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Detalles Bibliográficos
Autores principales: Hong, Seung-Hyun, Lee, Kyu-Sun, Kwak, Su-Jin, Kim, Ae-Kyeong, Bai, Hua, Jung, Min-Su, Kwon, O-Yu, Song, Woo-Joo, Tatar, Marc, Yu, Kweon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410862/
https://www.ncbi.nlm.nih.gov/pubmed/22876196
http://dx.doi.org/10.1371/journal.pgen.1002857