An Induced Pocket for the Binding of Potent Fusion Inhibitor CL-385319 with H5N1 Influenza Virus Hemagglutinin

The influenza glycoprotein hemagglutinin (HA) plays crucial roles in the early stage of virus infection, including receptor binding and membrane fusion. Therefore, HA is a potential target for developing anti-influenza drugs. Recently, we characterized a novel inhibitor of highly pathogenic H5N1 inf...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Runming, Song, Deshou, Zhu, Zhibo, Xu, Hanhong, Liu, Shuwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410875/
https://www.ncbi.nlm.nih.gov/pubmed/22876294
http://dx.doi.org/10.1371/journal.pone.0041956

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410875/
https://www.ncbi.nlm.nih.gov/pubmed/22876294
http://dx.doi.org/10.1371/journal.pone.0041956

Ejemplares similares