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An Induced Pocket for the Binding of Potent Fusion Inhibitor CL-385319 with H5N1 Influenza Virus Hemagglutinin
The influenza glycoprotein hemagglutinin (HA) plays crucial roles in the early stage of virus infection, including receptor binding and membrane fusion. Therefore, HA is a potential target for developing anti-influenza drugs. Recently, we characterized a novel inhibitor of highly pathogenic H5N1 inf...
Autores principales: | Li, Runming, Song, Deshou, Zhu, Zhibo, Xu, Hanhong, Liu, Shuwen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410875/ https://www.ncbi.nlm.nih.gov/pubmed/22876294 http://dx.doi.org/10.1371/journal.pone.0041956 |
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