Ubiquitin-Associated (UBA) Domain in Human Fas Associated Factor 1 Inhibits Tumor Formation by Promoting Hsp70 Degradation

Human Fas associated factor 1 (hFAF1) is a pro-apoptotic scaffolding protein containing ubiquitin-associating (UBA), ubiquitin like 1 and 2 (UBL1, UBL2), and ubiquitin regulatory X (UBX) domains. hFAF1 interacts with polyubiquitinated proteins via its N-terminal UBA domain and with valosin containin...

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Detalles Bibliográficos
Autores principales: Lee, Jae-Jin, Kim, Young Mee, Jeong, Jaeho, Bae, Duk Soo, Lee, Kong-Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410879/
https://www.ncbi.nlm.nih.gov/pubmed/22876279
http://dx.doi.org/10.1371/journal.pone.0040361

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410879/
https://www.ncbi.nlm.nih.gov/pubmed/22876279
http://dx.doi.org/10.1371/journal.pone.0040361

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