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Ubiquitin-Associated (UBA) Domain in Human Fas Associated Factor 1 Inhibits Tumor Formation by Promoting Hsp70 Degradation
Human Fas associated factor 1 (hFAF1) is a pro-apoptotic scaffolding protein containing ubiquitin-associating (UBA), ubiquitin like 1 and 2 (UBL1, UBL2), and ubiquitin regulatory X (UBX) domains. hFAF1 interacts with polyubiquitinated proteins via its N-terminal UBA domain and with valosin containin...
Autores principales: | Lee, Jae-Jin, Kim, Young Mee, Jeong, Jaeho, Bae, Duk Soo, Lee, Kong-Joo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410879/ https://www.ncbi.nlm.nih.gov/pubmed/22876279 http://dx.doi.org/10.1371/journal.pone.0040361 |
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