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MicroRNA-7 Inhibits Epithelial-to-Mesenchymal Transition and Metastasis of Breast Cancer Cells via Targeting FAK Expression

Focal adhesion kinase (FAK) is an important mediator of extracellular matrix integrin signaling, cell motility, cell proliferation and cell survival. Increased FAK expression is observed in a variety of solid human tumors and increased FAK expression and activity frequently correlate with metastatic...

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Detalles Bibliográficos
Autores principales: Kong, Xiangjun, Li, Gaopeng, Yuan, Yan, He, Yan, Wu, Xiaoli, Zhang, Weijie, Wu, Zhengsheng, Chen, Tingting, Wu, Wenyong, Lobie, Peter E., Zhu, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410899/
https://www.ncbi.nlm.nih.gov/pubmed/22876288
http://dx.doi.org/10.1371/journal.pone.0041523