IL-10 Suppression of NK/DC Crosstalk Leads to Poor Priming of MCMV-Specific CD4 T Cells and Prolonged MCMV Persistence

IL-10 is an anti-inflammatory cytokine that regulates the extent of host immunity to infection by exerting suppressive effects on different cell types. Herpes viruses induce IL-10 to modulate the virus-host balance towards their own benefit, resulting in prolonged virus persistence. To define the ce...

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Detalles Bibliográficos
Autores principales: Mandaric, Sanja, Walton, Senta M., Rülicke, Thomas, Richter, Kirsten, Girard-Madoux, Mathilde J. H., Clausen, Björn E., Zurunic, Antonija, Kamanaka, Masahito, Flavell, Richard A., Jonjic, Stipan, Oxenius, Annette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410900/
https://www.ncbi.nlm.nih.gov/pubmed/22876184
http://dx.doi.org/10.1371/journal.ppat.1002846

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410900/
https://www.ncbi.nlm.nih.gov/pubmed/22876184
http://dx.doi.org/10.1371/journal.ppat.1002846

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