Cargando…

IL-10 Suppression of NK/DC Crosstalk Leads to Poor Priming of MCMV-Specific CD4 T Cells and Prolonged MCMV Persistence

IL-10 is an anti-inflammatory cytokine that regulates the extent of host immunity to infection by exerting suppressive effects on different cell types. Herpes viruses induce IL-10 to modulate the virus-host balance towards their own benefit, resulting in prolonged virus persistence. To define the ce...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mandaric, Sanja, Walton, Senta M., Rülicke, Thomas, Richter, Kirsten, Girard-Madoux, Mathilde J. H., Clausen, Björn E., Zurunic, Antonija, Kamanaka, Masahito, Flavell, Richard A., Jonjic, Stipan, Oxenius, Annette
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410900/ https://www.ncbi.nlm.nih.gov/pubmed/22876184 http://dx.doi.org/10.1371/journal.ppat.1002846

Ejemplares similares

Synergistic infection of two viruses MCMV and SCMV increases the accumulations of both MCMV and MCMV-derived siRNAs in maize
por: Xia, Zihao, et al.
Publicado: (2016)

Glucocortiocoid Treatment of MCMV Infected Newborn Mice Attenuates CNS Inflammation and Limits Deficits in Cerebellar Development
por: Kosmac, Kate, et al.
Publicado: (2013)

Galectin-3 Deficiency Facilitates TNF-α-Dependent Hepatocyte Death and Liver Inflammation in MCMV Infection
por: Stojanovic, Bojana, et al.
Publicado: (2019)

Investigating the Dynamics of MCMV-Specific CD8(+) T Cell Responses in Individual Hosts
por: Gabel, Michael, et al.
Publicado: (2019)

The complex of MCMV proteins and MHC class I evades NK cell control and drives the evolution of virus-specific activating Ly49 receptors
por: Železnjak, Jelena, et al.
Publicado: (2019)

UL36 Rescues Apoptosis Inhibition and In vivo Replication of a Chimeric MCMV Lacking the M36 Gene
por: Chaudhry, M. Zeeshan, et al.
Publicado: (2017)

NK Cell–Like Behavior of Vα14i NK T Cells during MCMV Infection
por: Wesley, Johnna D., et al.
Publicado: (2008)

Systemic Hematogenous Maintenance of Memory Inflation by MCMV Infection
por: Smith, Corinne J., et al.
Publicado: (2014)

An adjuvanted inactivated murine cytomegalovirus (MCMV) vaccine induces potent and long-term protective immunity against a lethal challenge with virulent MCMV
por: Wang, Huadong, et al.
Publicado: (2014)

Tcf1(+) cells are required to maintain the inflationary T cell pool upon MCMV infection
por: Welten, Suzanne P. M., et al.
Publicado: (2020)

Deciphering the role of DC subsets in MCMV infection to better understand immune protection against viral infections
por: Alexandre, Yannick O., et al.
Publicado: (2014)

TNF Signaling Dictates Myeloid and Non-Myeloid Cell Crosstalk to Execute MCMV-Induced Extrinsic Apoptosis
por: Mandal, Pratyusha, et al.
Publicado: (2020)

The Impact of Ly49-NK Cell-Dependent Recognition of MCMV Infection on Innate and Adaptive Immune Responses
por: Pyzik, Michal, et al.
Publicado: (2011)

CD4 T Cell Responses in Latent and Chronic Viral Infections
por: Walton, Senta, et al.
Publicado: (2013)

Sex Bias in Susceptibility to MCMV Infection: Implication of TLR9
por: Traub, Stephanie, et al.
Publicado: (2012)

γδ T Cells Confer Protection against Murine Cytomegalovirus (MCMV)
por: Khairallah, Camille, et al.
Publicado: (2015)

MCMV Centrifugal Enhancement: A New Spin on an Old Topic
por: Hancock, Trevor J., et al.
Publicado: (2021)

Comparison of the pathogenesis of the highly passaged MCMV Smith strain with that of the low passaged MCMV HaNa1 isolate in BALB/c mice upon oronasal inoculation
por: Zhang, Shunchuan, et al.
Publicado: (2015)

Reduced MCMV Δm157 viral clearance in the absence of TSAd
por: Moussa, P., et al.
Publicado: (2015)

Ly49C-Dependent Control of MCMV Infection by NK Cells Is Cis-Regulated by MHC Class I Molecules
por: Forbes, Catherine A., et al.
Publicado: (2014)

Increased Viral Dissemination in the Brain and Lethality in MCMV-Infected, Dicer-Deficient Neonates
por: Ostermann, Eleonore, et al.
Publicado: (2015)

Inflammasome activation in mouse inner ear in response to MCMV induced hearing loss
por: Shi, Xi, et al.
Publicado: (2015)

Laboratory diagnostics of murine blood for detection of mouse cytomegalovirus (MCMV)-induced hepatitis
por: Stahl, Felix R., et al.
Publicado: (2018)

In silico MCMV Silencing Concludes Potential Host-Derived miRNAs in Maize
por: Iqbal, Muhammad Shahzad, et al.
Publicado: (2017)

Influenza- and MCMV-induced memory CD8 T cells control respiratory vaccinia virus infection despite residence in distinct anatomical niches
por: Welten, Suzanne P. M., et al.
Publicado: (2021)

MCMV-mediated Inhibition of the Pro-apoptotic Bak Protein Is Required for Optimal In Vivo Replication
por: Fleming, Peter, et al.
Publicado: (2013)

Increasing inflationary T-cell responses following transient depletion of MCMV-specific memory T cells
por: Sims, Stuart, et al.
Publicado: (2015)

MCMV Dissemination from Latently-Infected Allografts Following Transplantation into Pre-Tolerized Recipients
por: Shah, Sahil, et al.
Publicado: (2020)

MCMV-based vaccine vectors expressing full-length viral proteins provide long-term humoral immune protection upon a single-shot vaccination
por: Kim, Yeonsu, et al.
Publicado: (2022)

A Modified Screening System for Loss-of-Function and Dominant Negative Alleles of Essential MCMV Genes
por: Pogoda, Madlen, et al.
Publicado: (2014)

Glial cell activation, recruitment, and survival of B-lineage cells following MCMV brain infection
por: Lokensgard, James R., et al.
Publicado: (2016)

Proteomic Changes during MCMV Infection Revealed by iTRAQ Quantitative Proteomic Analysis in Maize
por: Dang, Mingqing, et al.
Publicado: (2019)

Don’t Go Breaking My Heart: MCMV as a Model for HCMV-Associated Cardiovascular Diseases
por: Bonavita, Cassandra M., et al.
Publicado: (2021)

MCMV induces neointima in IFN-γR-/- mice: Intimal cell apoptosis and persistent proliferation of myofibroblasts
por: Hamamdzic, Damir, et al.
Publicado: (2001)

Neutrophils Recruited by IL-22 in Peripheral Tissues Function as TRAIL-Dependent Antiviral Effectors against MCMV
por: Stacey, Maria A., et al.
Publicado: (2014)

Absence of Siglec-H in MCMV Infection Elevates Interferon Alpha Production but Does Not Enhance Viral Clearance
por: Puttur, Franz, et al.
Publicado: (2013)

Inflammation and outer blood-retina barrier (BRB) compromise following choroidal murine cytomegalovirus (MCMV) infections
por: Xu, Jinxian, et al.
Publicado: (2018)

The Role of Caspase-12 in Retinal Bystander Cell Death and Innate Immune Responses against MCMV Retinitis
por: Zhang, Xinyan, et al.
Publicado: (2021)

Absence of Cross-Presenting Cells in the Salivary Gland and Viral Immune Evasion Confine Cytomegalovirus Immune Control to Effector CD4 T Cells
por: Walton, Senta M., et al.
Publicado: (2011)

Cross-Presentation of a Spread-Defective MCMV Is Sufficient to Prime the Majority of Virus-Specific CD8+ T Cells
por: Snyder, Christopher M., et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_2nis54vj3sa8eo4r52a4ishcs9