The Importance of GLUT3 for De Novo Lipogenesis in Hypoxia-Induced Lipid Loading of Human Macrophages

Atherosclerotic lesions are characterized by lipid-loaded macrophages (foam cells) and hypoxic regions. Although it is well established that foam cells are produced by uptake of cholesterol from oxidized LDL, we previously showed that hypoxia also promotes foam cell formation even in the absence of...

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Detalles Bibliográficos
Autores principales: Li, Lu, Liu, Bo, Håversen, Liliana, Lu, Emma, Magnusson, Lisa U., Ståhlman, Marcus, Borén, Jan, Bergström, Göran, Levin, Malin C., Hultén, Lillemor Mattsson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410913/
https://www.ncbi.nlm.nih.gov/pubmed/22876317
http://dx.doi.org/10.1371/journal.pone.0042360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410913/
https://www.ncbi.nlm.nih.gov/pubmed/22876317
http://dx.doi.org/10.1371/journal.pone.0042360

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