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PNPLA3 gene-by-visceral adipose tissue volume interaction and the pathogenesis of fatty liver disease: The NHLBI Family Heart Study

BACKGROUND: Fatty liver disease (FLD) is characterized by increased intrahepatic triglyceride content with or without inflammation and is associated with obesity, and features of the metabolic syndrome. Several recent GWAS have reported an association between SNP rs738409 in the PNPLA3 gene and FLD....

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Detalles Bibliográficos
Autores principales: Graff, M., North, K.E., Franceschini, N., Reiner, A.P., Feitosa, M., Carr, J.J., Gordon-Larsen, P., Wojczynski, M. K., Borecki, I.B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410967/
https://www.ncbi.nlm.nih.gov/pubmed/22546774
http://dx.doi.org/10.1038/ijo.2012.65