Antagonism of NMDA receptors as a potential treatment for Down syndrome: a pilot randomized controlled trial

Down syndrome (DS) is the most common genetic cause of intellectual disability. The N-methyl-D-aspartate (NMDA) receptor uncompetitive antagonist, memantine hydrochloride (memantine), has been shown to improve learning/memory and rescue one form of hippocampus synaptic plasticity dysfunction in the...

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Detalles Bibliográficos
Autores principales: Boada, R, Hutaff-Lee, C, Schrader, A, Weitzenkamp, D, Benke, T A, Goldson, E J, Costa, A C S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410988/
https://www.ncbi.nlm.nih.gov/pubmed/22806212
http://dx.doi.org/10.1038/tp.2012.66

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410988/
https://www.ncbi.nlm.nih.gov/pubmed/22806212
http://dx.doi.org/10.1038/tp.2012.66

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